Foliar application with some amino acids provides plant with readymade nutrition, thus it has positive effect on plants metabolism with a corresponding promotion in crop quantity and quality. Thus, two field experiments were conducted at Kaha Vegetable Research Farm, Qalubia governorate, Egypt during the two successive winter seasons of 2013/2014 and 2014/2015 in a clayey loamy soil under flood irrigation system. Garlic (Allium sativum L.) cv. Sids 40 was used to study the effect of foliar application with three concentrations of each, moringa leaves extract (5, 10 and 15 g/ L), glutamine (50, 100 and 200 ppm) or cysteine (50, 100 and 200 ppm) on growth, yield, quality and gloves oil content. Gloves were planting at mid of September in both seasons. A Randomized Complete Block Design with three replications was used. The obtained results revealed that foliar spray with moringa leaves extract 10 g/ L, glutamine 200 ppm or cysteine 100 ppm treatments gave the highest values of plant growth criteria i.e. plant length, number of leaves/ plant, leaves chlorophyll content and leaves area of garlic at both seasons as compared to the other treatments and control. Concerning yield and yield components, spraying with moringa leaves extract 10 g/ L, glutamine 200 ppm or cysteine 100 ppm increased curing yield (ton/ fed.) by (59.4 %, 60.1 % and 59.2 %) and (42.1 %, 42.9 % and 41.9 %) and blubs dry matter % by (10.5 %, 11.7 % and 11.2 %) and (10.6 %, 10.1 % and 10.6 %) over the control, in the first and second seasons, respectively. Also, using the same above mentioned treatments were the best and gave significant increases of bulb quality (average cured bulb diameter and weight), chemical constitutes: K (%) and P (%,) total free amino acids (g/ 100 g dry weigh) and essential oil (mg/ kg dry weight). Results of the present work highlighted the positive effect of moringa leaves extract as natural substance and as it can mimic the role of synthetic amino acids, it could be applied safely (as plant foliar spray) for preserve human health and environment.